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Insights from Structures of Cancer-Relevant Pre-mRNA Splicing Factors
Pre-mRNA splicing factors recognize consensus signals within preliminary transcripts, and as cogs of the spliceosome machine, orchestrate the excision and rejoining of pre-mRNA regions for gene expression. Large-scale sequencing has demonstrated that mutations in key genes encoding pre-mRNA splicing...
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| Vydáno v: | Curr Opin Genet Dev |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871561/ https://ncbi.nlm.nih.gov/pubmed/29128695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.10.008 |
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