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Insights from Structures of Cancer-Relevant Pre-mRNA Splicing Factors

Pre-mRNA splicing factors recognize consensus signals within preliminary transcripts, and as cogs of the spliceosome machine, orchestrate the excision and rejoining of pre-mRNA regions for gene expression. Large-scale sequencing has demonstrated that mutations in key genes encoding pre-mRNA splicing...

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Detalhes bibliográficos
Publicado no:Curr Opin Genet Dev
Autor principal: Kielkopf, Clara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871561/
https://ncbi.nlm.nih.gov/pubmed/29128695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2017.10.008
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