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Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome

U12-type introns are a rare class of introns in the genomes of diverse eukaryotes. In the human genome, they number over 700. A subset of these introns has been shown to be spliced at a slower rate compared to the major U2-type introns. This suggests a rate-limiting regulatory function for the minor...

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Hlavní autoři: Niemelä, Elina H., Oghabian, Ali, Staals, Raymond H.J., Greco, Dario, Pruijn, Ger J.M., Frilander, Mikko J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066798/
https://ncbi.nlm.nih.gov/pubmed/24848017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku391
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