Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300

The E-protein transcription factors play essential roles in lymphopoiesis, with E12 and E47 (hereafter called E2A) being particularly important in B cell specification and maturation. The E2A gene is also involved in a chromosomal translocation that results in the leukemogenic oncoprotein E2A-PBX1....

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Bibliografski detalji
Glavni autori: Denis, Christopher M., Langelaan, David N., Kirlin, Alyssa C., Chitayat, Seth, Munro, Kim, Spencer, Holly L., LeBrun, David P., Smith, Steven P.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Structural Biology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066744/
https://ncbi.nlm.nih.gov/pubmed/24682819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku206
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