Functional redundancy between the transcriptional activation domains of E2A is mediated by binding to the KIX domain of CBP/p300

The E-protein transcription factors play essential roles in lymphopoiesis, with E12 and E47 (hereafter called E2A) being particularly important in B cell specification and maturation. The E2A gene is also involved in a chromosomal translocation that results in the leukemogenic oncoprotein E2A-PBX1....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Denis, Christopher M., Langelaan, David N., Kirlin, Alyssa C., Chitayat, Seth, Munro, Kim, Spencer, Holly L., LeBrun, David P., Smith, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066744/
https://ncbi.nlm.nih.gov/pubmed/24682819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku206
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados