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Comparison of non-canonical PAMs for CRISPR/Cas9-mediated DNA cleavage in human cells
CRISPR/Cas9 -mediated DNA cleavage (CCMDC) is becoming increasingly used for efficient genome engineering. Proto-spacer adjacent motif (PAM) adjacent to target sequence is one of the key components in the design of CCMDC strategies. It has been reported that NAG sequences are the predominant non-can...
Gorde:
| Egile Nagusiak: | , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4066725/ https://ncbi.nlm.nih.gov/pubmed/24956376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05405 |
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