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MYC Association with Cancer Risk and a New Model of MYC-Mediated Repression

MYC is one of the most frequently mutated and overexpressed genes in human cancer but the regulation of MYC expression and the ability of MYC protein to repress cellular genes (including itself) have remained mysterious. Recent genome-wide association studies show that many genetic polymorphisms ass...

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Detalhes bibliográficos
Autor principal: Cole, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066640/
https://ncbi.nlm.nih.gov/pubmed/24985129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014316
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