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Socializing with MYC: Cell Competition in Development and as a Model for Premalignant Cancer

Studies in Drosophila and mammals have made it clear that genetic mutations that arise in somatic tissues are rapidly recognized and eliminated, suggesting that cellular fitness is tightly monitored. During development, damaged, mutant, or otherwise unfit cells are prevented from contributing to the...

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Detalhes bibliográficos
Autor principal: Johnston, Laura A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968783/
https://ncbi.nlm.nih.gov/pubmed/24692189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014274
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