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Socializing with MYC: Cell Competition in Development and as a Model for Premalignant Cancer
Studies in Drosophila and mammals have made it clear that genetic mutations that arise in somatic tissues are rapidly recognized and eliminated, suggesting that cellular fitness is tightly monitored. During development, damaged, mutant, or otherwise unfit cells are prevented from contributing to the...
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| Format: | Artigo |
| Jezik: | Inglês |
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Cold Spring Harbor Laboratory Press
2014
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968783/ https://ncbi.nlm.nih.gov/pubmed/24692189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014274 |
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