Growth Suppression by Acute Promyelocytic Leukemia-Associated Protein PLZF Is Mediated by Repression of c-myc Expression

The transcriptional repressor PLZF was identified by its translocation with retinoic acid receptor alpha in t(11;17) acute promyelocytic leukemia (APL). Ectopic expression of PLZF leads to cell cycle arrest and growth suppression, while disruption of normal PLZF function is implicated in the develop...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: McConnell, Melanie J., Chevallier, Nathalie, Berkofsky-Fessler, Windy, Giltnane, Jena M., Malani, Rupal B., Staudt, Louis M., Licht, Jonathan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC309637/
https://ncbi.nlm.nih.gov/pubmed/14645547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.24.9375-9388.2003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados