Histone Acetyltransferase Activity of p300 Is Required for Transcriptional Repression by the Promyelocytic Leukemia Zinc Finger Protein

Histone acetyltransferase (HAT) activities of proteins such as p300, CBP, and P/CAF play important roles in activation of gene expression. We now show that the HAT activity of p300 can also be required for down-regulation of transcription by a DNA binding repressor protein. Promyelocytic leukemia zi...

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Main Authors: Guidez, Fabien, Howell, Louise, Isalan, Mark, Cebrat, Marek, Alani, Rhoda M., Ivins, Sarah, Hormaeche, Itsaso, McConnell, Melanie J., Pierce, Sarah, Cole, Philip A., Licht, Jonathan, Zelent, Arthur
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1156991/
https://ncbi.nlm.nih.gov/pubmed/15964811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.13.5552-5566.2005
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