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Conditional Genetic Interactions of RTT107, SLX4, and HRQ1 Reveal Dynamic Networks upon DNA Damage in S. cerevisiae

The DNA damage response (DDR) is a dynamic process that is crucial for protecting the cell from challenges to genome integrity. Although many genome-wide studies in Saccharomyces cerevisiae have identified genes that contribute to resistance to DNA-damaging agents, more work is needed to elucidate t...

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Main Authors: Leung, Grace P., Aristizabal, Maria J., Krogan, Nevan J., Kobor, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065249/
https://ncbi.nlm.nih.gov/pubmed/24700328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.114.011205
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