Loss of H3 K79 Trimethylation Leads to Suppression of Rtt107-dependent DNA Damage Sensitivity through the Translesion Synthesis Pathway

Genomic integrity is maintained by the coordinated interaction of many DNA damage response pathways, including checkpoints, DNA repair processes, and cell cycle restart. In Saccharomyces cerevisiae, the BRCA1 C-terminal domain-containing protein Rtt107/Esc4 is required for restart of DNA replication...

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Bibliografiska uppgifter
Huvudupphovsmän: Lévesque, Nancy, Leung, Grace P., Fok, Alexandra K., Schmidt, Thorsten I., Kobor, Michael S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2010
Ämnen:
DNA and Chromosomes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966125/
https://ncbi.nlm.nih.gov/pubmed/20810656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116855
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