Replisome-mediated Translesion Synthesis and Leading Strand Template Lesion Skipping Are Competing Bypass Mechanisms

A number of different enzymatic pathways have evolved to ensure that DNA replication can proceed past template base damage. These pathways include lesion skipping by the replisome, replication fork regression followed by either correction of the damage and origin-independent replication restart or h...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Gabbai, Carolina B., Yeeles, Joseph T. P., Marians, Kenneth J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
DNA and Chromosomes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239630/
https://ncbi.nlm.nih.gov/pubmed/25301949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613257
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