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Replisome-mediated Translesion Synthesis and Leading Strand Template Lesion Skipping Are Competing Bypass Mechanisms

A number of different enzymatic pathways have evolved to ensure that DNA replication can proceed past template base damage. These pathways include lesion skipping by the replisome, replication fork regression followed by either correction of the damage and origin-independent replication restart or h...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Gabbai, Carolina B., Yeeles, Joseph T. P., Marians, Kenneth J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239630/
https://ncbi.nlm.nih.gov/pubmed/25301949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613257
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