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Replisome-mediated Translesion Synthesis and Leading Strand Template Lesion Skipping Are Competing Bypass Mechanisms

A number of different enzymatic pathways have evolved to ensure that DNA replication can proceed past template base damage. These pathways include lesion skipping by the replisome, replication fork regression followed by either correction of the damage and origin-independent replication restart or h...

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Vydáno v:J Biol Chem
Hlavní autoři: Gabbai, Carolina B., Yeeles, Joseph T. P., Marians, Kenneth J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239630/
https://ncbi.nlm.nih.gov/pubmed/25301949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613257
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