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Dynamics of Leading-strand Lesion Skipping by the Replisome
The E. coli replisome stalls transiently when it encounters a lesion in the leading-strand template, skipping over the damage by reinitiating replication at a new primer synthesized downstream by the primase. We report here that template unwinding and lagging-strand synthesis continue downstream of...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877186/ https://ncbi.nlm.nih.gov/pubmed/24268579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.020 |
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