Selective vulnerability of dentate granule cells prior to amyloid deposition in PDAPP mice: Digital morphometric analyses

Increasing evidence from mouse models of Alzheimer's disease shows that overexpression of a mutant form of the amyloid precursor protein (APP) and its product, β-amyloid peptide, initiate pathological changes before amyloid deposition. To evaluate the cytological basis for one of these early ch...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wu, Chi-Cheng, Chawla, Faisal, Games, Dora, Rydel, Russell E., Freedman, Stephen, Schenk, Dale, Young, Warren G., Morrison, John H., Bloom, Floyd E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC406479/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15118092/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402147101
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