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Oncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapy

Oncolytic viruses (OV) are a class of antitumor agents that selectively kill tumor cells while sparing normal cells. Oncolytic herpes simplex virus (oHSV) has been investigated in clinical trials for patients with the malignant brain tumor glioblastoma for more than a decade. These clinical studies...

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Bibliografiske detaljer
Main Authors: Ning, Jianfang, Wakimoto, Hiroaki
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064532/
https://ncbi.nlm.nih.gov/pubmed/24999342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00303
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