Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

BACKGROUND: Improved methods are required to screen drug candidates for their influences on protein interactions. There is also a compelling need for miniaturization of screening assays, with attendant reductions in reagent consumption and assay costs. METHODS: We used sensitive, miniaturized proxim...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gustafsdottir, Sigrun M., Wennström, Stefan, Fredriksson, Simon, Schallmeiner, Edith, Hamilton, Andrew D., Sebti, Said M., Landegren, Ulf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064371/
https://ncbi.nlm.nih.gov/pubmed/18499900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2007.099424
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