Use of Proximity Ligation to Screen for Inhibitors of Interactions between Vascular Endothelial Growth Factor A and Its Receptors

BACKGROUND: Improved methods are required to screen drug candidates for their influences on protein interactions. There is also a compelling need for miniaturization of screening assays, with attendant reductions in reagent consumption and assay costs. METHODS: We used sensitive, miniaturized proxim...

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Main Authors: Gustafsdottir, Sigrun M., Wennström, Stefan, Fredriksson, Simon, Schallmeiner, Edith, Hamilton, Andrew D., Sebti, Said M., Landegren, Ulf
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064371/
https://ncbi.nlm.nih.gov/pubmed/18499900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2007.099424
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