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Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation

High-throughput prioritization of cancer-causing mutations (drivers) is a key challenge of cancer genome projects, due to the number of somatic variants detected in tumors. One important step in this task is to assess the functional impact of tumor somatic mutations. A number of computational method...

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Bibliografski detalji
Glavni autori: Gonzalez-Perez, Abel, Deu-Pons, Jordi, Lopez-Bigas, Nuria
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064314/
https://ncbi.nlm.nih.gov/pubmed/23181723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm390
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