Many Ribosomal Protein Genes Are Cancer Genes in Zebrafish

We have generated several hundred lines of zebrafish (Danio rerio), each heterozygous for a recessive embryonic lethal mutation. Since many tumor suppressor genes are recessive lethals, we screened our colony for lines that display early mortality and/or gross evidence of tumors. We identified 12 li...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Amsterdam, Adam, Sadler, Kirsten C, Lai, Kevin, Farrington, Sarah, Bronson, Roderick T, Lees, Jacqueline A, Hopkins, Nancy
Formato: Artigo
Idioma:Inglês
Publicado em: PLOS 2004
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC406397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15138505/
https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020139
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