The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas

BACKGROUND: There is a body of evidence that shows a link between tumorigenesis and ribosome biogenesis. The precursor of mature 18S, 28S and 5.8S ribosomal RNAs is transcribed from the ribosomal DNA gene (rDNA), which exists as 300–400 copies in the human diploid genome. Approximately one half of t...

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Hlavní autoři: Bacalini, Maria Giulia, Pacilli, Annalisa, Giuliani, Cristina, Penzo, Marianna, Treré, Davide, Pirazzini, Chiara, Salvioli, Stefano, Franceschi, Claudio, Montanaro, Lorenzo, Garagnani, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062283/
https://ncbi.nlm.nih.gov/pubmed/24884608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-361
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