Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells

The alterations of ribosome biogenesis and protein synthesis play a direct role in the development of tumors. The accessibility and transcription of ribosomal genes is controlled at several levels, with their epigenetic regulation being one of the most important. Here we explored the JmjC domain-con...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Galbiati, Alice, Penzo, Marianna, Bacalini, Maria Giulia, Onofrillo, Carmine, Guerrieri, Ania Naila, Garagnani, Paolo, Franceschi, Claudio, Treré, Davide, Montanaro, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514893/
https://ncbi.nlm.nih.gov/pubmed/28415746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16181
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