Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells

The alterations of ribosome biogenesis and protein synthesis play a direct role in the development of tumors. The accessibility and transcription of ribosomal genes is controlled at several levels, with their epigenetic regulation being one of the most important. Here we explored the JmjC domain-con...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Galbiati, Alice, Penzo, Marianna, Bacalini, Maria Giulia, Onofrillo, Carmine, Guerrieri, Ania Naila, Garagnani, Paolo, Franceschi, Claudio, Treré, Davide, Montanaro, Lorenzo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514893/
https://ncbi.nlm.nih.gov/pubmed/28415746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16181
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