Epigenetic up-regulation of ribosome biogenesis and more aggressive phenotype triggered by the lack of the histone demethylase JHDM1B in mammary epithelial cells

The alterations of ribosome biogenesis and protein synthesis play a direct role in the development of tumors. The accessibility and transcription of ribosomal genes is controlled at several levels, with their epigenetic regulation being one of the most important. Here we explored the JmjC domain-con...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Galbiati, Alice, Penzo, Marianna, Bacalini, Maria Giulia, Onofrillo, Carmine, Guerrieri, Ania Naila, Garagnani, Paolo, Franceschi, Claudio, Treré, Davide, Montanaro, Lorenzo
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514893/
https://ncbi.nlm.nih.gov/pubmed/28415746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16181
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