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The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas
BACKGROUND: There is a body of evidence that shows a link between tumorigenesis and ribosome biogenesis. The precursor of mature 18S, 28S and 5.8S ribosomal RNAs is transcribed from the ribosomal DNA gene (rDNA), which exists as 300–400 copies in the human diploid genome. Approximately one half of t...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062283/ https://ncbi.nlm.nih.gov/pubmed/24884608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-361 |
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