Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation

Dyskerin is a nucleolar protein encoded by the DKC1 gene that (i) stabilizes the RNA component of the telomerase complex, and (ii) drives the site-specific pseudouridilation of rRNA. It is known that the partial lack of dyskerin function causes a defect in the translation of a subgroup of mRNAs cont...

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Detalhes bibliográficos
Main Authors: Rocchi, Laura, Pacilli, Annalisa, Sethi, Rajni, Penzo, Marianna, Schneider, Robert J., Treré, Davide, Brigotti, Maurizio, Montanaro, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783170/
https://ncbi.nlm.nih.gov/pubmed/23821664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt587
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