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Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation
Dyskerin is a nucleolar protein encoded by the DKC1 gene that (i) stabilizes the RNA component of the telomerase complex, and (ii) drives the site-specific pseudouridilation of rRNA. It is known that the partial lack of dyskerin function causes a defect in the translation of a subgroup of mRNAs cont...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783170/ https://ncbi.nlm.nih.gov/pubmed/23821664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt587 |
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