DKC1 Overexpression Induces a More Aggressive Cellular Behavior and Increases Intrinsic Ribosomal Activity in Immortalized Mammary Gland Cells

SIMPLE SUMMARY: Dyskerin is a nucleolar protein involved in the modification and processing of ribosomal RNA and in the stabilization of the telomerase RNA component. In several human tumors, including breast cancer, dyskerin overexpression is found related to patients’ worse prognosis. Our aim was...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Guerrieri, Ania Naila, Zacchini, Federico, Onofrillo, Carmine, Di Viggiano, Sara, Penzo, Marianna, Ansuini, Alessio, Gandin, Ilaria, Nobe, Yuko, Taoka, Masato, Isobe, Toshiaki, Treré, Davide, Montanaro, Lorenzo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760958/
https://ncbi.nlm.nih.gov/pubmed/33255756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123512
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