DKC1 Overexpression Induces a More Aggressive Cellular Behavior and Increases Intrinsic Ribosomal Activity in Immortalized Mammary Gland Cells

SIMPLE SUMMARY: Dyskerin is a nucleolar protein involved in the modification and processing of ribosomal RNA and in the stabilization of the telomerase RNA component. In several human tumors, including breast cancer, dyskerin overexpression is found related to patients’ worse prognosis. Our aim was...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Guerrieri, Ania Naila, Zacchini, Federico, Onofrillo, Carmine, Di Viggiano, Sara, Penzo, Marianna, Ansuini, Alessio, Gandin, Ilaria, Nobe, Yuko, Taoka, Masato, Isobe, Toshiaki, Treré, Davide, Montanaro, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7760958/
https://ncbi.nlm.nih.gov/pubmed/33255756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12123512
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