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Mechanism of Raloxifene-induced Upregulation of Glutamate TransporterS in Rat Primary Astrocytes

Raloxifene (RX), a selective estrogen receptor modulator (SERM), exerts neuroprotection in multiple clinical and experimental settings. Astrocytic glutamate transporters GLT-1 (EAAT2) and GLAST (EAAT1) are the main glutamate transporters in the central nervous system, taking up most of excess glutam...

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Detalhes bibliográficos
Main Authors: Karki, Pratap, Webb, Anton, Zerguine, Abdelbassat, Choi, Joseph, Son, Deok-Soo, Lee, Eunsook
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061260/
https://ncbi.nlm.nih.gov/pubmed/24782323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22679
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