A short-term model of COPD identifies a role for mast cell tryptase

BACKGROUND: Cigarette smoke-induced chronic obstructive pulmonary disease (COPD) is a life-threatening inflammatory disorder of the lung. The development of effective therapies for COPD has been hampered by the lack of an animal model that mimics the human disease in a short time-frame. OBJECTIVES:...

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Autors principals: Beckett, Emma L., Stevens, Richard L., Jarnicki, Andrew G., Kim, Richard Y., Hanish, Irwan, Hansbro, Nicole G., Deane, Andrew, Keely, Simon, Horvat, Jay C., Yang, Ming, Oliver, Brian G., van Rooijen, Nico, Inman, Mark D., Adachi, Roberto, Soberman, Roy J., Hamadi, Sahar, Wark, Peter A., Foster, Paul S., Hansbro, Philip M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060894/
https://ncbi.nlm.nih.gov/pubmed/23380220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.11.053
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