A short-term model of COPD identifies a role for mast cell tryptase

BACKGROUND: Cigarette smoke-induced chronic obstructive pulmonary disease (COPD) is a life-threatening inflammatory disorder of the lung. The development of effective therapies for COPD has been hampered by the lack of an animal model that mimics the human disease in a short time-frame. OBJECTIVES:...

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Détails bibliographiques
Auteurs principaux: Beckett, Emma L., Stevens, Richard L., Jarnicki, Andrew G., Kim, Richard Y., Hanish, Irwan, Hansbro, Nicole G., Deane, Andrew, Keely, Simon, Horvat, Jay C., Yang, Ming, Oliver, Brian G., van Rooijen, Nico, Inman, Mark D., Adachi, Roberto, Soberman, Roy J., Hamadi, Sahar, Wark, Peter A., Foster, Paul S., Hansbro, Philip M.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060894/
https://ncbi.nlm.nih.gov/pubmed/23380220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.11.053
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