Essential role for mast cell tryptase in acute experimental colitis

Patients with inflammatory bowel disease (IBD) have increased numbers of human tryptase-β (hTryptase-β)-positive mast cells (MCs) in the gastrointestinal tract. The amino acid sequence of mouse mast cell protease (mMCP)-6 is most similar to that of hTryptase-β. We therefore hypothesized that this mM...

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Autori principali: Hamilton, Matthew J., Sinnamon, Mark J., Lyng, Gregory D., Glickman, Jonathan N., Wang, Xueli, Xing, Wei, Krilis, Steven A., Blumberg, Richard S., Adachi, Roberto, Lee, David M., Stevens, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017166/
https://ncbi.nlm.nih.gov/pubmed/21173247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005758108
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