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Mast Cell Tryptase Deficiency Attenuates Mouse Abdominal Aortic Aneurysm Formation

RATIONALE: Mast cells (MCs) contribute to formation of abdominal aortic aneurysms (AAAs) by producing biologically active mediators. Tryptase is the most abundant MC granule protein and participates in MC activation, protease maturation, leukocyte recruitment, and angiogenesis — all processes critic...

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Main Authors: Zhang, Jie, Sun, Jiusong, Lindholt, Jes S., Sukhova, Galina K., Sinnamon, Mark, Stevens, Richard L., Adachi, Roberto, Libby, Peter, Thompson, Robert W., Shi, Guo-Ping
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108141/
https://ncbi.nlm.nih.gov/pubmed/21493897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.243758
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