A short-term model of COPD identifies a role for mast cell tryptase

BACKGROUND: Cigarette smoke-induced chronic obstructive pulmonary disease (COPD) is a life-threatening inflammatory disorder of the lung. The development of effective therapies for COPD has been hampered by the lack of an animal model that mimics the human disease in a short time-frame. OBJECTIVES:...

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Main Authors: Beckett, Emma L., Stevens, Richard L., Jarnicki, Andrew G., Kim, Richard Y., Hanish, Irwan, Hansbro, Nicole G., Deane, Andrew, Keely, Simon, Horvat, Jay C., Yang, Ming, Oliver, Brian G., van Rooijen, Nico, Inman, Mark D., Adachi, Roberto, Soberman, Roy J., Hamadi, Sahar, Wark, Peter A., Foster, Paul S., Hansbro, Philip M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060894/
https://ncbi.nlm.nih.gov/pubmed/23380220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.11.053
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