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Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a chelation strategy aimed at reducing oxidative damage associated with regional iron deposition without affecting circulating metals. Translational cell and animal models provided concept proofs and a delayed...

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Bibliografiske detaljer
Main Authors: Devos, David, Moreau, Caroline, Devedjian, Jean Christophe, Kluza, Jérome, Petrault, Maud, Laloux, Charlotte, Jonneaux, Aurélie, Ryckewaert, Gilles, Garçon, Guillaume, Rouaix, Nathalie, Duhamel, Alain, Jissendi, Patrice, Dujardin, Kathy, Auger, Florent, Ravasi, Laura, Hopes, Lucie, Grolez, Guillaume, Firdaus, Wance, Sablonnière, Bernard, Strubi-Vuillaume, Isabelle, Zahr, Noel, Destée, Alain, Corvol, Jean-Christophe, Pöltl, Dominik, Leist, Marcel, Rose, Christian, Defebvre, Luc, Marchetti, Philippe, Cabantchik, Z. Ioav, Bordet, Régis
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060813/
https://ncbi.nlm.nih.gov/pubmed/24251381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5593
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