Ceruloplasmin activity and iron chelation treatment of patients with Parkinson’s disease

BACKGROUND: Growing body of evidence suggests that Parkinson’s disease (PD) is associated with oxidative damage via iron accumulation in the substantia nigra (SN). Low ceruloplasmin (CP)-ferroxidase activity has been identified in the SN and the cerebrospinal fluid (CSF) of patients with PD. The iro...

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Pubblicato in:BMC Neurol
Autori principali: Grolez, Guillaume, Moreau, Caroline, Sablonnière, Bernard, Garçon, Guillaume, Devedjian, Jean-Christophe, Meguig, Sayah, Gelé, Patrick, Delmaire, Christine, Bordet, Regis, Defebvre, Luc, Cabantchik, Ioav Z, Devos, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429376/
https://ncbi.nlm.nih.gov/pubmed/25943368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-015-0331-3
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