Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a chelation strategy aimed at reducing oxidative damage associated with regional iron deposition without affecting circulating metals. Translational cell and animal models provided concept proofs and a delayed...

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Detalhes bibliográficos
Main Authors: Devos, David, Moreau, Caroline, Devedjian, Jean Christophe, Kluza, Jérome, Petrault, Maud, Laloux, Charlotte, Jonneaux, Aurélie, Ryckewaert, Gilles, Garçon, Guillaume, Rouaix, Nathalie, Duhamel, Alain, Jissendi, Patrice, Dujardin, Kathy, Auger, Florent, Ravasi, Laura, Hopes, Lucie, Grolez, Guillaume, Firdaus, Wance, Sablonnière, Bernard, Strubi-Vuillaume, Isabelle, Zahr, Noel, Destée, Alain, Corvol, Jean-Christophe, Pöltl, Dominik, Leist, Marcel, Rose, Christian, Defebvre, Luc, Marchetti, Philippe, Cabantchik, Z. Ioav, Bordet, Régis
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Original Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060813/
https://ncbi.nlm.nih.gov/pubmed/24251381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5593
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