Could Conservative Iron Chelation Lead to Neuroprotection in Amyotrophic Lateral Sclerosis?

Iron accumulation has been observed in mouse models and in both sporadic and familial forms of amyotrophic lateral sclerosis (ALS). Iron chelation could reduce iron accumulation and the related excess of oxidative stress in the motor pathways. However, classical iron chelation would induce systemic...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Moreau, Caroline, Danel, Véronique, Devedjian, Jean Christophe, Grolez, Guillaume, Timmerman, Kelly, Laloux, Charlotte, Petrault, Maud, Gouel, Flore, Jonneaux, Aurélie, Dutheil, Mary, Lachaud, Cédrick, Lopes, Renaud, Kuchcinski, Grégory, Auger, Florent, Kyheng, Maeva, Duhamel, Alain, Pérez, Thierry, Pradat, Pierre François, Blasco, Hélène, Veyrat-Durebex, Charlotte, Corcia, Philippe, Oeckl, Patrick, Otto, Markus, Dupuis, Luc, Garçon, Guillaume, Defebvre, Luc, Cabantchik, Z. Ioav, Duce, James, Bordet, Régis, Devos, David
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
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News & Views
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067092/
https://ncbi.nlm.nih.gov/pubmed/29287521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7493
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