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Differential Requirement for CD70 and CD80/CD86 in Dendritic Cell-mediated Activation of Tumor Tolerized CD8 T Cells
A major obstacle to efficacious T cell-based cancer immunotherapy is the tolerizing tumor microenvironment that rapidly inactivates tumor-infiltrating lymphocytes. In an autochthonous model of prostate cancer, we have previously shown that intratumoral injection of antigen loaded dendritic cells (DC...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060810/ https://ncbi.nlm.nih.gov/pubmed/22798683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201271 |
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