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Activation of Tolerogenic Dendritic Cells in the Tumor Draining Lymph Nodes by CD8(+) T Cells Engineered to Express CD40 Ligand

Tolerogenic dendritic cells in the tumor microenvironment can inhibit the generation and maintenance of robust anti-tumor T cell responses. Here, we investigated the effects of local delivery of CD40 ligand (CD40L) by tumor-reactive CD8(+) T cells on dendritic cell activation and anti-tumor T cell r...

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書誌詳細
主要な著者: Higham, Eileen M., Wittrup, K. Dane, Chen, Jianzhu
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843821/
https://ncbi.nlm.nih.gov/pubmed/20200275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903111
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