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Activation of Tolerogenic Dendritic Cells in the Tumor Draining Lymph Nodes by CD8(+) T Cells Engineered to Express CD40 Ligand
Tolerogenic dendritic cells in the tumor microenvironment can inhibit the generation and maintenance of robust anti-tumor T cell responses. Here, we investigated the effects of local delivery of CD40 ligand (CD40L) by tumor-reactive CD8(+) T cells on dendritic cell activation and anti-tumor T cell r...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2010
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843821/ https://ncbi.nlm.nih.gov/pubmed/20200275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903111 |
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