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Differential Requirement for CD70 and CD80/CD86 in Dendritic Cell-mediated Activation of Tumor Tolerized CD8 T Cells
A major obstacle to efficacious T cell-based cancer immunotherapy is the tolerizing tumor microenvironment that rapidly inactivates tumor-infiltrating lymphocytes. In an autochthonous model of prostate cancer, we have previously shown that intratumoral injection of antigen loaded dendritic cells (DC...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060810/ https://ncbi.nlm.nih.gov/pubmed/22798683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201271 |
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