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Highly enantioselective synthesis of γ-, δ-, and ε-chiral 1-alkanols via Zr-catalyzed asymmetric carboalumination of alkenes (ZACA)–Cu- or Pd-catalyzed cross-coupling

Despite recent advances of asymmetric synthesis, the preparation of enantiomerically pure (≥99% ee) compounds remains a challenge in modern organic chemistry. We report here a strategy for a highly enantioselective (≥99% ee) and catalytic synthesis of various γ- and more-remotely chiral alcohols fro...

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書誌詳細
主要な著者: Xu, Shiqing, Oda, Akimichi, Kamada, Hirofumi, Negishi, Ei-ichi
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060698/
https://ncbi.nlm.nih.gov/pubmed/24912191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401187111
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