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Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)

Although it is widely known that trimethylamine N-oxide (TMAO), an osmolyte used by nature, stabilizes the folded state of proteins, the underlying mechanism of action is not entirely understood. To gain further insight into this important biological phenomenon, we use the C≡N stretching vibration o...

詳細記述

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書誌詳細
主要な著者: Ma, Jianqiang, Pazos, Ileana M., Gai, Feng
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060645/
https://ncbi.nlm.nih.gov/pubmed/24912147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403224111
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