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Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)

Although it is widely known that trimethylamine N-oxide (TMAO), an osmolyte used by nature, stabilizes the folded state of proteins, the underlying mechanism of action is not entirely understood. To gain further insight into this important biological phenomenon, we use the C≡N stretching vibration o...

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Detalhes bibliográficos
Main Authors: Ma, Jianqiang, Pazos, Ileana M., Gai, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060645/
https://ncbi.nlm.nih.gov/pubmed/24912147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403224111
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