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Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)

Although it is widely known that trimethylamine N-oxide (TMAO), an osmolyte used by nature, stabilizes the folded state of proteins, the underlying mechanism of action is not entirely understood. To gain further insight into this important biological phenomenon, we use the C≡N stretching vibration o...

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Bibliografski detalji
Glavni autori: Ma, Jianqiang, Pazos, Ileana M., Gai, Feng
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060645/
https://ncbi.nlm.nih.gov/pubmed/24912147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403224111
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