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Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO)
Although it is widely known that trimethylamine N-oxide (TMAO), an osmolyte used by nature, stabilizes the folded state of proteins, the underlying mechanism of action is not entirely understood. To gain further insight into this important biological phenomenon, we use the C≡N stretching vibration o...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060645/ https://ncbi.nlm.nih.gov/pubmed/24912147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403224111 |
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