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5-Hydroxymethylcytosine: generation, fate, and genomic distribution
5-Methylcytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian cells by the ten-eleven translocation (Tet) family of dioxygenases. While 5mC has been extensively studied, we have just started to understand the distribution and function of 5hmC in mammalian genomes. Despite th...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060438/ https://ncbi.nlm.nih.gov/pubmed/23498661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.02.017 |
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