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5-Hydroxymethylcytosine: generation, fate, and genomic distribution

5-Methylcytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian cells by the ten-eleven translocation (Tet) family of dioxygenases. While 5mC has been extensively studied, we have just started to understand the distribution and function of 5hmC in mammalian genomes. Despite th...

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Detalhes bibliográficos
Main Authors: Shen, Li, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060438/
https://ncbi.nlm.nih.gov/pubmed/23498661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2013.02.017
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