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Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma

RNA interference (RNAi) allows the specific knockdown of tumor relevant genes. To induce RNAi, the delivery of small interfering RNAs (siRNAs) is of crucial importance. This is particularly challenging for their therapeutic applications in vivo. Low molecular weight branched polyethylenimine (PEI) i...

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書誌詳細
主要な著者: Höbel, Sabrina, Appeldoorn, Chantal C.M., Gaillard, Pieter J., Aigner, Achim
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060103/
https://ncbi.nlm.nih.gov/pubmed/27721338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4121591
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