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Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma

RNA interference (RNAi) allows the specific knockdown of tumor relevant genes. To induce RNAi, the delivery of small interfering RNAs (siRNAs) is of crucial importance. This is particularly challenging for their therapeutic applications in vivo. Low molecular weight branched polyethylenimine (PEI) i...

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Bibliografische gegevens
Hoofdauteurs: Höbel, Sabrina, Appeldoorn, Chantal C.M., Gaillard, Pieter J., Aigner, Achim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060103/
https://ncbi.nlm.nih.gov/pubmed/27721338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4121591
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