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Jun kinase-induced overexpression of leukemia-associated Rho GEF (LARG) mediates sustained hypercontraction of longitudinal smooth muscle in inflammation

The signaling pathways mediating sustained contraction of mouse colonic longitudinal smooth muscle and the mechanisms involved in hypercontractility of this muscle layer in response to cytokines and TNBS-induced colitis have not been fully explored. In control longitudinal smooth muscle cells, ACh a...

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Detalhes bibliográficos
Main Authors: Al-Shboul, Othman, Nalli, Ancy D., Kumar, Divya P., Zhou, Ruizhe, Mahavadi, Sunila, Kuemmerle, John F., Grider, John R., Murthy, Karnam S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060000/
https://ncbi.nlm.nih.gov/pubmed/24740538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00021.2014
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