Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury

A reversible inhibition of mitochondrial respiration by complex I inhibition at the onset of reperfusion decreases injury in buffer-perfused hearts. Administration of acidic reperfusate for a brief period at reperfusion decreases cardiac injury. We asked if acidification treatment decreased cardiac...

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Autors principals: Xu, Aijun, Szczepanek, Karol, Maceyka, Michael W., Ross, Thomas, Bowler, Elizabeth, Hu, Ying, Kenny, Barrett, Mehfoud, Chris, Desai, Pooja N., Baumgarten, Clive M., Chen, Qun, Lesnefsky, Edward J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059999/
https://ncbi.nlm.nih.gov/pubmed/24696146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00241.2013
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